Home Online Features Data from First-in-Human Trial targeting CISH, a Novel Immune Checkpoint, in Patients with Metastatic Colorectal Cancer Presented at 2025 American Association for Cancer Research (AACR) Annual Meeting

Data from First-in-Human Trial targeting CISH, a Novel Immune Checkpoint, in Patients with Metastatic Colorectal Cancer Presented at 2025 American Association for Cancer Research (AACR) Annual Meeting

Hand-out

Press Releases

May 1, 2025

Data from First-in-Human Trial targeting CISH, a Novel Immune Checkpoint, in Patients with Metastatic Colorectal Cancer Presented at 2025 American Association for Cancer Research (AACR) Annual Meeting

By Intima Bioscience

Study Administered CRISPR genetically engineered CISH-knockout Tumor Infiltrating Lymphocytes as a Model System to Evaluate the Safety and Efficacy of this Classically Undruggable Intracellular Target

{"bradfordera-website":"Website"}

The Bradford Era

Local & Social

{"bradfordera-website":"Website"}

Lifestyles

Brother’s beliefs are incompatible with sister’s reality

April 5, 2026

DEAR ABBY: My son is getting married next year. He and his future wife are extremely religious. My daughter (his sister) is also engaged — to a wonder...

{"to-print":"To print", "bradfordera-website":"Website"}

Local News

April support groups, education classes at BRMC, OGH

April 4, 2026

Bradford Regional Medical Center and Olean General Hospital, Kaleida Health facilities, will offer several community classes and support groups throug...

Local News

AMERICA250PA – Did you know?

April 4, 2026

(Editor’s note: America250PA - McKean County provided the material featured here, created by the McKean County Planning Commission — Chairman Gregory ...

{"newsletter-daily-headlines":"Daily Headlines", "newsletters":"Newsletters", "to-print":"To print", "bradfordera-website":"Website"}

Lifestyles

Cleaning ovens with tablets

April 4, 2026

Dear Heloise: Greasy oven buildup used to take far too much time and effort to clean, especially after heavy cooking days. I found a much easier metho...

{"to-print":"To print", "bradfordera-website":"Website"}

Round the Square

‘Round the Square: A special Easter trip, part 2 of 2

April 4, 2026

EASTER 2: And now the second part of Virginia Loveland's account of the Bradford senior trip to Washington, D.C. We left off with a visit to the Burea...

This Week's Ads

Current e-Edition

Already a subscriber? Click the image to view the latest e-edition.

Don't have a subscription? Click here to see our subscription options.

Mobile App

Download Now

The Bradford Era mobile app brings you the latest local breaking news, updates, and more. Read the Bradford Era on your mobile device just as it appears in print.

Newsletters for You

Sign Up for Our Newsletters

Daily Headlines

Obituaries

Sports

Help Our Community

Please help local businesses by taking an online survey to help us navigate through these unprecedented times. None of the responses will be shared or used for any other purpose except to better serve our community. The survey is at: www.pulsepoll.com $1,000 is being awarded. Everyone completing the survey will be able to enter a contest to Win as our way of saying, "Thank You" for your time. Thank You!