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    Home News Piscitelli part of longevity research
    Piscitelli part of longevity research
    News
    BRIAN LOTHRIDGEEra Reporter  
    October 24, 2007

    Piscitelli part of longevity research

    When you meet Jim Piscitelli, you may be surprised to learn that
    he is pushing 100 years old.

    He can move about his house without much difficulty, looks to be
    in fine physical health, and has a memory as clear as day.

    On the phone or in the supermarket, Piscitelli has frequently
    been told that he looks and sounds much younger than he is.

    “I get that constantly,” said the 97-year-old. “I don’t know
    what to attribute it to.”

    That attribution is the subject of The Long Life Family Study,
    an international research project sponsored by the National
    Institute on Aging of the National Institutes of Health. Families
    from the U.S. and Denmark who have several members reaching very
    old ages are being studied to find out why some people live until a
    very old age and why some families maintain their health far longer
    than the average family. Researchers seek to improve the health of
    future generations, and help older people maintain their health and
    well-being in the future.

    The five-year, ,18 million study is a collaboration between,
    Columbia University of New York, N.Y., University of Pittsburgh,
    Boston (Mass.) University Medical Center, University of Southern
    Denmark, Odense, Denmark, and the Washington University School of
    Medicine, St. Louis, Mo.

    Increasing evidence shows that exceptional longevity and
    exceptional survival traits are clustered in families. Siblings of
    the exceptionally old have an increased chance of surviving much
    longer than the average population, according to the University of
    Pittsburgh Epidemiology Department. There is also evidence that
    genetics may be responsible for some of the familial clustering of
    exceptional longevity. Researchers are analyzing the vitals, life
    habits and DNA, among other factors to determine why the
    Piscitellis and other families have lived so long, said Nancy W.
    Glynn, Ph.D., research assistant professor of Epidemiology at the
    university.

    The Piscitelli family became involved with the study after
    Piscitelli’s daughter, Barbara, saw an article in an Australian
    publication about longevity problems and a new study on families
    who are aging well. Barbara Piscitelli, 59, who lives in Australia,
    contacted the National Institute on the Aging to see how her
    family could become involved in the study.

    A team from the University of Pittsburgh came to Jim
    Piscitelli’s home Nov. 14, 2006, for a three-hour examination which
    included filling out a series of questionnaires and some
    performance and physical assessments. A blood sample was taken to
    obtain information about genetics. The research team is also
    looking at close to 40 of Piscitelli’s relatives. Seven of 10 of
    his siblings are still alive with ages ranging from 80 to 96. The
    team came to the home of Piscitelli’s niece, Anne Herzing of St.
    Marys, July 22.

    The university hopes to obtain information from about 250
    families over three years. It is already one-third of the way
    there, Glynn said. To qualify, a family must have two living
    siblings around 90 or older, and at least one offspring of a
    sibling participate in the study. Additional family members can
    also be a part of the study. Younger generations are studied to
    determine the importance of genetics in longevity.

    “We’d love to find a million Piscitelli families,” Glynn said.
    “The Piscitellis were a big family and we very much enjoyed seeing
    them.”

    The University of Pittsburgh was chosen to participate in the
    project through a competitive process, Glynn said. The university
    had to submit an application that included a position paper on how
    they would approach the study. All the universities chosen focus on
    different areas of Epidemiology and bring different strengths to
    the table, Glynn said.

    Researchers are seeking more families to participate in the
    study, Glynn said. There is no cost to participating in the study
    and those who do will be compensated ,25 for their time and
    participation upon completion of the in-person visit. People will
    get blood test results including total cholesterol,
    HDL-cholesterol, LDL-cholesterol, blood glucose, trigylcerides, and
    kidney function levels. They will also get blood pressure results,
    height, weight, grip strength, and lung function test results.
    People will also be notified if test results for hemoglobin levels,
    white blood cell count or platelet count are extremely
    abnormal.

    Jim Piscitelli said keeping active may be what has kept him in
    good health for so long. He has held various positions, from a
    pattern maker for Hanley Brick Co. to foreman in Dresser
    Manufacturing’s quality control department. He umpired minor league
    baseball games and refereed high school football games for years
    and continues to be involved in organizations such as the Exchange
    Club of America, Area Transport Authority and the Knights of
    Columbus.

    “I’ve been active all my life,” he said. “I’ve kept myself in
    good shape all these years.”

    His advice for a long life?

    “You have to be nice to people, that’s number one,” Piscitelli
    said. “Keep busy. Help the poor. Don’t sit around, keep yourself
    occupied with something.”

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