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Fentanyl has had a deadly impact on Pennsylvania, and state Auditor General Eugene A. DePasquale on Wednesday said more needs to be done to prevent overdoses and save lives.

Looking for a warm, furry friend to keep you company when the weather gets cold? The McKean County SPCA has a wide variety of pet-worthy creatures looking for a good home.

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Pennsylvania residents can set their snow boots aside for a bit longer, as the area will not see a significant amount of snow anytime soon.

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Autumn is associated with many things, such as Halloween, bonfires and pumpkin spice everything, though for many, the best part about the season is observing the gorgeous array of colors the changing fall foliage has to offer.

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HARRISBURG, Pa. (AP) — These Pennsylvania lotteries were drawn Saturday:

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Chief executives of a handful of pharmaceutical and drug distribution companies are negotiating with government attorneys to see if they can reach a settlement ahead of the first federal trial over the nation's opioid crisis.

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DAYTONA BEACH, Fla. (AP) — NASCAR closed its $2 billion purchase of International Speedway Corp. on Friday, bringing under the sanctioning body's control 12 tracks that include Daytona, Talladega and Miami-Homestead Speedway.

We’ve all experienced sticker shock. It’s one thing to gasp over the cost of a new dishwasher, but sticker shock for those who need to purchase medications for a chronic disease such as diabetes is a serious issue.

Vaping has come of age in the most perfect of social conditions. Smoking cigarettes is falling out of favor socially and even among nicotine users, and is wholly rejected by many young people today. To get their fix they're turning to what is marketed as a cleaner and safer method of ingestion. Enticing flavors, edgy technology and social media are empowering the tobacco industry to ensnare a new generation with nicotine addiction
by way of vaping. And it’s working. In 2016, 43.8% of high schoolers in New York state tried vaping, more than double the total two years prior. This trend has Ontario County officials deeply concerned.

Commonly known as ALS, the condition is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, and it is always fatal. The affected motor neurons deteriorate and the brain and spinal cord lose their ability to send signals to muscles, which begin to atrophy. As muscles lose nourishment, those affected lose their ability to speak, move, eat and breathe. The average life expectancy of those afflicted with ALS is two to five years, and there is no cure.

Project Fit America is a charity that works alongside educators to create opportunities for kids to stay active and healthy. It offers fitness grants and programs to help fund resources such as equipment, teacher training and curriculum. The goal is not only to get students involved physically, but also nurture an environment in which children enjoy living a healthy lifestyle. For the past five years at Homer-Center Elementary, in Homer City, Pennsylvania, that opportunity to stay active has been the Lub Dub Run Club.

The United Auto Workers’ strike against General Motors may be nearing an end after a month after it was announced late Wednesday a tentative agreement had been reached. One day later, however, that announcement might prove premature.

AKCAKALE, Turkey (AP) — Turkish-backed Syrian fighters clashed with Kurdish-led forces in several parts of northeastern Syria on Saturday, with some crossing the border from Turkey to attack a village, a war monitor said. Both sides blamed each other for fighting that has rattled the U.S.-br…

LONDON (AP) — Prime Minister Boris Johnson's plan to get Parliament to approve his divorce deal with the European Union was thrown into doubt Saturday, as lawmakers were first given a vote on whether — yet again — to delay their final decision on Brexit.

MIDWAY ATOLL, Northwestern Hawaiian Islands (AP) — Deep-sea explorers scouring the world's oceans for sunken World War II ships are focusing in on debris fields deep in the Pacific, in an area where one of the most decisive battles of the time took place.